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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CREBBP
All Species:
10.91
Human Site:
T251
Identified Species:
20
UniProt:
Q92793
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92793
NP_001073315.1
2442
265351
T251
T
Q
V
S
P
Q
M
T
G
H
A
G
L
N
T
Chimpanzee
Pan troglodytes
XP_523285
2442
265358
T251
T
Q
V
S
P
Q
M
T
G
H
A
G
L
N
T
Rhesus Macaque
Macaca mulatta
XP_001095225
2442
265320
T251
T
Q
V
S
P
Q
M
T
G
H
A
G
L
N
T
Dog
Lupus familis
XP_851777
2404
260682
A251
T
Q
V
S
P
Q
M
A
S
H
A
G
L
N
T
Cat
Felis silvestris
Mouse
Mus musculus
P45481
2441
265456
A250
T
Q
V
S
P
Q
M
A
G
H
A
G
L
N
T
Rat
Rattus norvegicus
NP_596872
2444
265618
A250
T
Q
V
S
P
Q
M
A
G
H
A
G
L
N
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_414964
2447
266615
A237
T
Q
V
S
P
Q
M
A
G
H
T
G
L
N
T
Frog
Xenopus laevis
NP_001088637
2428
264402
P244
T
Q
G
T
A
T
M
P
T
H
A
G
M
T
T
Zebra Danio
Brachydanio rerio
NP_001082924
2111
234059
Q173
E
N
A
N
K
H
N
Q
Q
P
M
L
S
P
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524642
3276
340709
S341
M
Q
M
T
Q
L
N
S
L
P
Y
G
V
G
Q
Honey Bee
Apis mellifera
XP_001122031
2606
284119
I257
M
G
P
N
T
Q
G
I
H
H
P
S
G
P
H
Nematode Worm
Caenorhab. elegans
P34545
2056
227161
Q118
S
N
N
S
P
R
P
Q
A
Y
P
P
G
Q
Q
Sea Urchin
Strong. purpuratus
XP_782558
2635
288594
G321
G
Q
P
N
M
I
S
G
M
D
P
A
M
A
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
99.4
93.9
N.A.
94.8
95.8
N.A.
N.A.
88
76
61.5
N.A.
36.5
42.7
30.5
38.5
Protein Similarity:
100
99.9
99.6
95.5
N.A.
96.4
97.2
N.A.
N.A.
92
83.3
68.8
N.A.
46.7
54.7
43.9
50.9
P-Site Identity:
100
100
100
86.6
N.A.
93.3
93.3
N.A.
N.A.
86.6
46.6
0
N.A.
13.3
13.3
13.3
6.6
P-Site Similarity:
100
100
100
86.6
N.A.
93.3
93.3
N.A.
N.A.
86.6
60
6.6
N.A.
40
20
33.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
8
0
0
31
8
0
54
8
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% D
% Glu:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
8
8
0
0
0
8
8
47
0
0
70
16
8
0
% G
% His:
0
0
0
0
0
8
0
0
8
70
0
0
0
0
8
% H
% Ile:
0
0
0
0
0
8
0
8
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
8
% K
% Leu:
0
0
0
0
0
8
0
0
8
0
0
8
54
0
0
% L
% Met:
16
0
8
0
8
0
62
0
8
0
8
0
16
0
0
% M
% Asn:
0
16
8
24
0
0
16
0
0
0
0
0
0
54
0
% N
% Pro:
0
0
16
0
62
0
8
8
0
16
24
8
0
16
8
% P
% Gln:
0
77
0
0
8
62
0
16
8
0
0
0
0
8
16
% Q
% Arg:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% R
% Ser:
8
0
0
62
0
0
8
8
8
0
0
8
8
0
0
% S
% Thr:
62
0
0
16
8
8
0
24
8
0
8
0
0
8
62
% T
% Val:
0
0
54
0
0
0
0
0
0
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
8
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _